KEGG   REACTION: R01463
Entry
R01463                      Reaction                               
Name
cholesterol,NADPH-hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating)
Definition
Cholesterol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 7alpha-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00187 + C00007 + C03024 <=> C03594 + C03161 + C00001
Reaction class
RC00524  C00187_C03594
Enzyme
1.14.14.23
Pathway
rn00120  Primary bile acid biosynthesis
rn01100  Metabolic pathways
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.23
     R01463  Cholesterol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 7alpha-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K00489  cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
Other DBs
RHEA: 21815

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
   SABIO-RK (1)   
Gene (494)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (493)   
All databases (509)   

Download RDF
DBGET integrated database retrieval system